Yann Ilboudo

Yann Ilboudo

PhD candidate in Bioinformatics

University of Montréal

Biography

PhD candidate at the university of Montreal studying the genetic heterogeneity in sickle cell disease. Under the supervision of Guillaume Lettre at Montreal Heart Institute

Download my resumé.

Interests

  • Bioinformatics
  • Hematology
  • Artificial Intelligence

Education

  • PhD in Bioinformatics, 2020 - Present

    University of Montreal

  • MSc in Bioinformatics, 2015 - 2017

    University of Montreal

  • BSc in Bioengineering, 2007 - 2011

    SUNY Binghamton

Publications

Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis

Using MR, we tested the causal relationship between l-glutamine levels and painful crises in SCD patients.
DOI Blood Cells, Molecules, and Diseases 2020
Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis

A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients.

We tested the association of a common PIEZO1 variants with red blood cell density, hemolytic parameters, estimated glomerular filtration rate (eGFR), and SCD clinical complications.
DOI American Journal of Hematology 2018

Genome-wide association study of erythrocyte density in sickle cell disease patients.

We performed the first genome-wide association study for red cell density (DRBC) identify new genes involved in RBC hydration in SCD in 374 sickle cell anemia patients.
DOI Blood Cells, Molecules, and Diseases 2017

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.

Designing a variant-aware library we investigated the role DNA regulatory elements.
DOI Nature Genetics 2017

Talks

Causal role of L-glutamine and 3-ureidopropionate in sickle cell disease complications: A Mendelian randomization analysis (Poster Presentation)

In 2017, the FDA approved for the first time in 20 years a new drug to treat sickle cell disease (SCD). The drug, Endari, is an oral …
Oct 15, 2019 12:00 AM — Oct 19, 2019 12:00 AM George R. Brown Convention Center
Poster

Metabolite Signatures of Organ Dysfunction in Sickle Cell Disease Patients. (Poster Presentation)

Sickle cell disease (SCD) is a monogenic disease caused by mutations in the β-globin gene. The complications related to the disease are …
Apr 30, 2018 12:00 AM — May 1, 2018 12:00 AM CHU Sainte-Justine
Poster

Metabolomics in Sickle Cell Disease: Searching for severity biomarkers. (Oral Presentation)

Sickle cell disease (SCD) is a monogenic disease caused by mutations in the β-globin gene. The complications related to the disease are …
Jan 8, 2018 12:00 AM — Jan 9, 2018 12:00 AM Centre de Recherche
Slides

Trans-ethnic meta-analysis of fetal hemoglobin genome-wide association results identifies common variants at the KLF1 locus. (Poster Presentation)

The clinical severity of sickle cell disease (SCD) and β-thalassemia, the major hemoglobinopathies that aff ect millions of patients …
Oct 17, 2017 12:00 AM — Oct 21, 2017 12:00 AM Orange County Convention Center, South Building
Poster

The genetics of red blood cell density in sickle cell disease patients. (Poster Presentation)

Sickle cell disease is a monogenic blood disorder caused by mutations in the β-globin gene. Although a single gene is involved in this …
Oct 18, 2016 12:00 AM — Oct 22, 2016 12:00 AM Vancouver Convention Centre
Poster
See all talks

Awards & Accomplishments

Bourse de Mérite

University of Montreal Sep 2020
Bourses de Mérite aux cycles supérieurs

Bourse d’exemption UdeM

University of Montreal May 2016 – Mar 2017
Bourse d’exemption UdeM pour étudiants internationaux

Getting and Cleaning Data

Coursera Dec 2014
See certificate

Commencement Speaker

SUNY-Binghamton May 2011 – May 2011
Professional Schools Student Speakers at Binghamton University Commencement Ceremony

Posts

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Last updated on Oct 28, 2020 1 min read

Relevant experiences

 
 
 
 
 

Moniteur de recherche

Montreal Heart Institute

Mar 2017 – Dec 2020 Montreal

Responsibilities include:

  • Analysing, and modelling genomics and metabolomics data

Contact